Proof of dual-topology architecture of Fluc F(-) channels with monobody blockers

Fluc-type F(-) channels — used by microorganisms for resisting fluoride toxicity — are unusual in their quaternary architecture: They are thought to associate as dimers with the two subunits in antiparallel transmembrane orientation. Here we subject this unusual structural feature to a direct test....

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Detalles Bibliográficos
Autores principales: Stockbridge, Randy B., Koide, Akiko, Miller, Christopher, Koide, Shohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265568/
https://www.ncbi.nlm.nih.gov/pubmed/25290819
http://dx.doi.org/10.1038/ncomms6120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265568/
https://www.ncbi.nlm.nih.gov/pubmed/25290819
http://dx.doi.org/10.1038/ncomms6120

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