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Proof of dual-topology architecture of Fluc F(-) channels with monobody blockers
Fluc-type F(-) channels — used by microorganisms for resisting fluoride toxicity — are unusual in their quaternary architecture: They are thought to associate as dimers with the two subunits in antiparallel transmembrane orientation. Here we subject this unusual structural feature to a direct test....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265568/ https://www.ncbi.nlm.nih.gov/pubmed/25290819 http://dx.doi.org/10.1038/ncomms6120 |