Facile construction of substituted pyrimido[4,5-d]pyrimidones by transformation of enaminouracil

The reaction of 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (1) as a binucleophile with primary aromatic or heterocyclic amines and formaldehyde or aromatic (heterocyclic) aldehydes in a molar ratio (1:1:2) gave the pyrimido[4,5-d]pyrimidin-2,4-dione ring systems 2–5. Treatment of 1 with diamine...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamama, Wafaa S., Ismail, Mohamed A., Al-Saman, Hanaa A., Zoorob, Hanafi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265671/
https://www.ncbi.nlm.nih.gov/pubmed/25685408
http://dx.doi.org/10.1016/j.jare.2012.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265671/
https://www.ncbi.nlm.nih.gov/pubmed/25685408
http://dx.doi.org/10.1016/j.jare.2012.01.001

Ejemplares similares