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Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization

Although important for gene regulation, most studies of genome organization use either fluorescence in situ hybridization (FISH) or chromosome conformation capture (3C) methods. FISH directly visualizes the spatial relationship of sequences but is usually applied to a few loci at a time. The frequen...

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Detalles Bibliográficos
Autores principales: Williamson, Iain, Berlivet, Soizik, Eskeland, Ragnhild, Boyle, Shelagh, Illingworth, Robert S., Paquette, Denis, Dostie, Josée, Bickmore, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265680/
https://www.ncbi.nlm.nih.gov/pubmed/25512564
http://dx.doi.org/10.1101/gad.251694.114