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GSK-3β Inhibition Attenuates CLP-Induced Liver Injury by Reducing Inflammation and Hepatic Cell Apoptosis

Liver dysfunction has been known to occur frequently in cases of sepsis. Excessive inflammation and apoptosis are pathological features of acute liver failure. Recent studies suggest that activation of glycogen synthase kinase- (GSK-) 3β is involved in inflammation and apoptosis. We aimed to investi...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Wang, Wenjie, Fang, Haoshu, Yang, Yan, Li, Xiaolan, He, Junli, Jiang, Xiaojing, Wang, Weipeng, Liu, Shenpei, Hu, Jifa, Liu, Anding, Dahmen, Uta, Dirsch, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265684/
https://www.ncbi.nlm.nih.gov/pubmed/25525303
http://dx.doi.org/10.1155/2014/629507