Cargando…

GSK-3β Inhibition Attenuates CLP-Induced Liver Injury by Reducing Inflammation and Hepatic Cell Apoptosis

Liver dysfunction has been known to occur frequently in cases of sepsis. Excessive inflammation and apoptosis are pathological features of acute liver failure. Recent studies suggest that activation of glycogen synthase kinase- (GSK-) 3β is involved in inflammation and apoptosis. We aimed to investi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hui, Wang, Wenjie, Fang, Haoshu, Yang, Yan, Li, Xiaolan, He, Junli, Jiang, Xiaojing, Wang, Weipeng, Liu, Shenpei, Hu, Jifa, Liu, Anding, Dahmen, Uta, Dirsch, Olaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265684/ https://www.ncbi.nlm.nih.gov/pubmed/25525303 http://dx.doi.org/10.1155/2014/629507

Ejemplares similares

Ischemic preconditioning attenuates ischemia/reperfusion injury in rat steatotic liver: role of heme oxygenase-1-mediated autophagy
por: Liu, Anding, et al.
Publicado: (2016)

Oxidation of HMGB1 Causes Attenuation of Its Pro-Inflammatory Activity and Occurs during Liver Ischemia and Reperfusion
por: Liu, Anding, et al.
Publicado: (2012)

Young plasma reverses age‐dependent alterations in hepatic function through the restoration of autophagy
por: Liu, Anding, et al.
Publicado: (2017)

Baicalein pretreatment reduces liver ischemia/reperfusion injury via induction of autophagy in rats
por: Liu, Anding, et al.
Publicado: (2016)

Granulocyte Colony Stimulating Factor Induces Lipopolysaccharide (LPS) Sensitization via Upregulation of LPS Binding Protein in Rat
por: Fang, Haoshu, et al.
Publicado: (2013)

The severity of LPS induced inflammatory injury is negatively associated with the functional liver mass after LPS injection in rat model
por: Fang, Haoshu, et al.
Publicado: (2018)

The LPS Responsiveness in BN and LEW Rats and Its Severity Are Modulated by the Liver
por: Fang, Haoshu, et al.
Publicado: (2018)

Modulation of Innate Immunity by G-CSF and Inflammatory Response by LBPK95A Improves the Outcome of Sepsis in a Rat Model
por: Fang, Haoshu, et al.
Publicado: (2018)

Effects of Lipopolysaccharide-Binding Protein (LBP) Single Nucleotide Polymorphism (SNP) in Infections, Inflammatory Diseases, Metabolic Disorders and Cancers
por: Meng, Leilei, et al.
Publicado: (2021)

Release of Danger Signals during Ischemic Storage of the Liver: A Potential Marker of Organ Damage?
por: Liu, Anding, et al.
Publicado: (2010)

Corrigendum to “Release of Danger Signals during Ischemic Storage of the Liver: A Potential Marker of Organ Damage?”
por: Liu, Anding, et al.
Publicado: (2022)

Balancing Innate Immunity and Inflammatory State via Modulation of Neutrophil Function: A Novel Strategy to Fight Sepsis
por: Fang, Haoshu, et al.
Publicado: (2015)

FK866 attenuates acute hepatic failure through c-jun-N-terminal kinase (JNK)-dependent autophagy
por: Guo, Enshuang, et al.
Publicado: (2017)

Identification of Proteins Interacting with Cytoplasmic High-Mobility Group Box 1 during the Hepatocellular Response to Ischemia Reperfusion Injury
por: Zhang, Tianjiao, et al.
Publicado: (2017)

Modulation of Autophagy: A Novel “Rejuvenation” Strategy for the Aging Liver
por: Xu, Fengming, et al.
Publicado: (2021)

Blocking autophagy with chloroquine aggravates lipid accumulation and reduces intracellular energy synthesis in hepatocellular carcinoma cells, both contributing to its anti-proliferative effect
por: Xu, Fengming, et al.
Publicado: (2022)

Size of portally deprived liver lobe after portal vein ligation and additional partial hepatectomy: Result of balancing proliferation and apoptosis
por: Wei, Weiwei, et al.
Publicado: (2020)

Effectiveness of Organ Donation Information Campaigns in Germany: A Facebook Based Online Survey
por: Terbonssen, Tobias, et al.
Publicado: (2015)

Registration of histological whole slide images guided by vessel structures
por: Schwier, Michael, et al.
Publicado: (2013)

The Role of Autophagy for the Regeneration of the Aging Liver
por: Xu, Fengming, et al.
Publicado: (2020)

A comparison of sampling strategies for histological image analysis
por: Homeyer, André, et al.
Publicado: (2012)

How Does a Single Cell Know When the Liver Has Reached Its Correct Size?
por: Hohmann, Nadine, et al.
Publicado: (2014)

Evaluation of Somatostatin and CXCR4 Receptor Expression in a Large Set of Prostate Cancer Samples Using Tissue Microarrays and Well-Characterized Monoclonal Antibodies
por: Werner, Christoph, et al.
Publicado: (2020)

Collagen-Like Proteins (ClpA, ClpB, ClpC, and ClpD) Are Required for Biofilm Formation and Adhesion to Plant Roots by Bacillus amyloliquefaciens FZB42
por: Zhao, Xia, et al.
Publicado: (2015)

Selective gene expression profiling contributes to a better understanding of the molecular pathways underlying the histological changes observed after RHMVL
por: Arlt, Janine, et al.
Publicado: (2022)

ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP
por: Kim, Sora, et al.
Publicado: (2020)

Genome-wide analysis of rice ClpB/HSP100, ClpC and ClpD genes
por: Singh, Amanjot, et al.
Publicado: (2010)

Cholestasis‐induced adaptive remodeling of interlobular bile ducts
por: Vartak, Nachiket, et al.
Publicado: (2016)

Biocellulose for Incisional Hernia Repair—An Experimental Pilot Study
por: Rauchfuß, Falk, et al.
Publicado: (2019)

Additional partial hepatectomy at the time of portal vein ligation accelerates the regeneration of the future liver remnant
por: Hua, Chuanfeng, et al.
Publicado: (2021)

Caseinolytic Proteins (Clp) in the Genus Klebsiella: Special Focus on ClpK
por: Motiwala, Tehrim, et al.
Publicado: (2021)

A fast and robust hepatocyte quantification algorithm including vein processing
por: Ivanovska, Tetyana, et al.
Publicado: (2010)

Assembly and proteolytic processing of mycobacterial ClpP1 and ClpP2
por: Benaroudj, Nadia, et al.
Publicado: (2011)

Bioinformatic identification of ClpI, a distinct class of Clp unfoldases in Actinomycetota
por: Jiang, Jialiu, et al.
Publicado: (2023)

Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven inflammation
por: Liu, Feng, et al.
Publicado: (2020)

The Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ClpC1
por: Leodolter, Julia, et al.
Publicado: (2015)

Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets
por: Kaemmerer, Daniel, et al.
Publicado: (2017)

The Bacterial ClpXP-ClpB Family Is Enriched with RNA-Binding Protein Complexes
por: Auburger, Georg, et al.
Publicado: (2022)

Antibiotic Acyldepsipeptides Stimulate the Streptomyces Clp-ATPase/ClpP Complex for Accelerated Proteolysis
por: Reinhardt, Laura, et al.
Publicado: (2022)

Dexmedetomidine Ameliorate CLP-Induced Rat Intestinal Injury via Inhibition of Inflammation
por: Chen, Yanqing, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jb0tfleuvgsuo7uair3qpmq8hl