Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3(+) Treg cells

Adoptive transfer of antigen-specific, in vitro-induced Foxp3(+) Treg (iTreg) cells protects against autoimmune disease. To generate antigen-specific iTreg cells at high purity, however, remains a challenge. Whereas polyclonal T cell stimulation with anti-CD3 and anti-CD28 antibody yields Foxp3(+) i...

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Detalles Bibliográficos
Autores principales: Verhagen, Johan, Wraith, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265731/
https://www.ncbi.nlm.nih.gov/pubmed/25108241
http://dx.doi.org/10.1016/j.jim.2014.07.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265731/
https://www.ncbi.nlm.nih.gov/pubmed/25108241
http://dx.doi.org/10.1016/j.jim.2014.07.012

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