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Blockade of LFA-1 augments in vitro differentiation of antigen-induced Foxp3(+) Treg cells
Adoptive transfer of antigen-specific, in vitro-induced Foxp3(+) Treg (iTreg) cells protects against autoimmune disease. To generate antigen-specific iTreg cells at high purity, however, remains a challenge. Whereas polyclonal T cell stimulation with anti-CD3 and anti-CD28 antibody yields Foxp3(+) i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265731/ https://www.ncbi.nlm.nih.gov/pubmed/25108241 http://dx.doi.org/10.1016/j.jim.2014.07.012 |