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CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain

The multi-domain CX3CL1 transmembrane chemokine triggers leukocyte adherence without rolling and migration by presenting its chemokine domain (CD) to its receptor CX3CR1. Through the combination of functional adhesion assays with structural analysis using FRAP, we investigated the functional role of...

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Detalles Bibliográficos
Autores principales: Ostuni, Mariano A., Guellec, Julie, Hermand, Patricia, Durand, Pauline, Combadière, Christophe, Pincet, Frédéric, Deterre, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265755/
https://www.ncbi.nlm.nih.gov/pubmed/25395671
http://dx.doi.org/10.1242/bio.20149845