Enhanced cytotoxic activity of cetuximab in EGFR-positive lung cancer by conjugating with gold nanoparticles

Cetuximab (C225) is a unique agent, targeting epidermal growth factor receptor (EGFR)-positive cancer. However, the therapeutic effect of C225 in EGFR high-expressing non-small cell lung cancer (NSCLC) remains poor. Here, we report that conjugation of C225 with gold nanoparticles (AuNPs) enhances th...

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Detalles Bibliográficos
Autores principales: Qian, Yichun, Qiu, Mantang, Wu, Qingquan, Tian, Yanyan, Zhang, Yu, Gu, Ning, Li, Suyi, Xu, Lin, Yin, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265789/
https://www.ncbi.nlm.nih.gov/pubmed/25502402
http://dx.doi.org/10.1038/srep07490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265789/
https://www.ncbi.nlm.nih.gov/pubmed/25502402
http://dx.doi.org/10.1038/srep07490

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