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Enhanced cytotoxic activity of cetuximab in EGFR-positive lung cancer by conjugating with gold nanoparticles

Cetuximab (C225) is a unique agent, targeting epidermal growth factor receptor (EGFR)-positive cancer. However, the therapeutic effect of C225 in EGFR high-expressing non-small cell lung cancer (NSCLC) remains poor. Here, we report that conjugation of C225 with gold nanoparticles (AuNPs) enhances th...

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Detalles Bibliográficos
Autores principales:	Qian, Yichun, Qiu, Mantang, Wu, Qingquan, Tian, Yanyan, Zhang, Yu, Gu, Ning, Li, Suyi, Xu, Lin, Yin, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265789/ https://www.ncbi.nlm.nih.gov/pubmed/25502402 http://dx.doi.org/10.1038/srep07490

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