CRISPR-Mediated Genomic Deletion of Sox2 in the Axolotl Shows a Requirement in Spinal Cord Neural Stem Cell Amplification during Tail Regeneration

The salamander is the only tetrapod that functionally regenerates all cell types of the limb and spinal cord (SC) and thus represents an important regeneration model, but the lack of gene-knockout technology has limited molecular analysis. We compared transcriptional activator-like effector nuclease...

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Detalles Bibliográficos
Autores principales: Fei, Ji-Feng, Schuez, Maritta, Tazaki, Akira, Taniguchi, Yuka, Roensch, Kathleen, Tanaka, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266004/
https://www.ncbi.nlm.nih.gov/pubmed/25241743
http://dx.doi.org/10.1016/j.stemcr.2014.06.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266004/
https://www.ncbi.nlm.nih.gov/pubmed/25241743
http://dx.doi.org/10.1016/j.stemcr.2014.06.018

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