Cargando…
CRISPR-Mediated Genomic Deletion of Sox2 in the Axolotl Shows a Requirement in Spinal Cord Neural Stem Cell Amplification during Tail Regeneration
The salamander is the only tetrapod that functionally regenerates all cell types of the limb and spinal cord (SC) and thus represents an important regeneration model, but the lack of gene-knockout technology has limited molecular analysis. We compared transcriptional activator-like effector nuclease...
Autores principales: | Fei, Ji-Feng, Schuez, Maritta, Tazaki, Akira, Taniguchi, Yuka, Roensch, Kathleen, Tanaka, Elly M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266004/ https://www.ncbi.nlm.nih.gov/pubmed/25241743 http://dx.doi.org/10.1016/j.stemcr.2014.06.018 |
Ejemplares similares
-
Live Imaging of Axolotl Digit Regeneration Reveals Spatiotemporal Choreography of Diverse Connective Tissue Progenitor Pools
por: Currie, Joshua D., et al.
Publicado: (2016) -
Germline Transgenic Methods for Tracking Cells and Testing Gene Function during Regeneration in the Axolotl
por: Khattak, Shahryar, et al.
Publicado: (2013) -
Germline Transgenic Methods for Tracking Cells and Testing Gene Function during Regeneration in the Axolotl
por: Khattak, Shahryar, et al.
Publicado: (2014) -
Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration
por: Rodrigo Albors, Aida, et al.
Publicado: (2015) -
Cellular dynamics underlying regeneration of appropriate segment number during axolotl tail regeneration
por: Vincent, Carr D., et al.
Publicado: (2015)