Transiently Active Wnt/β-Catenin Signaling Is Not Required but Must Be Silenced for Stem Cell Function during Muscle Regeneration

Adult muscle’s exceptional capacity for regeneration is mediated by muscle stem cells, termed satellite cells. As with many stem cells, Wnt/β-catenin signaling has been proposed to be critical in satellite cells during regeneration. Using new genetic reagents, we explicitly test in vivo whether Wnt/...

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Detalles Bibliográficos
Autores principales: Murphy, Malea M., Keefe, Alexandra C., Lawson, Jennifer A., Flygare, Steven D., Yandell, Mark, Kardon, Gabrielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266007/
https://www.ncbi.nlm.nih.gov/pubmed/25241745
http://dx.doi.org/10.1016/j.stemcr.2014.06.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266007/
https://www.ncbi.nlm.nih.gov/pubmed/25241745
http://dx.doi.org/10.1016/j.stemcr.2014.06.019

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