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Transiently Active Wnt/β-Catenin Signaling Is Not Required but Must Be Silenced for Stem Cell Function during Muscle Regeneration
Adult muscle’s exceptional capacity for regeneration is mediated by muscle stem cells, termed satellite cells. As with many stem cells, Wnt/β-catenin signaling has been proposed to be critical in satellite cells during regeneration. Using new genetic reagents, we explicitly test in vivo whether Wnt/...
Autores principales: | Murphy, Malea M., Keefe, Alexandra C., Lawson, Jennifer A., Flygare, Steven D., Yandell, Mark, Kardon, Gabrielle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266007/ https://www.ncbi.nlm.nih.gov/pubmed/25241745 http://dx.doi.org/10.1016/j.stemcr.2014.06.019 |
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