Transient p53 Suppression Increases Reprogramming of Human Fibroblasts without Affecting Apoptosis and DNA Damage

The discovery of human-induced pluripotent stem cells (iPSCs) has sparked great interest in the potential treatment of patients with their own in vitro differentiated cells. Recently, knockout of the Tumor Protein 53 (p53) gene was reported to facilitate reprogramming but unfortunately also led to g...

Descripción completa

Detalles Bibliográficos
Autores principales: Rasmussen, Mikkel A., Holst, Bjørn, Tümer, Zeynep, Johnsen, Mads G., Zhou, Shuling, Stummann, Tina C., Hyttel, Poul, Clausen, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266010/
https://www.ncbi.nlm.nih.gov/pubmed/25241739
http://dx.doi.org/10.1016/j.stemcr.2014.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266010/
https://www.ncbi.nlm.nih.gov/pubmed/25241739
http://dx.doi.org/10.1016/j.stemcr.2014.07.006

Ejemplares similares