Cargando…

Pim kinases in hematological malignancies: where are we now and where are we going?

The proviral insertion in murine (PIM) lymphoma proteins are a serine/threonine kinase family composed of three isoformes: Pim-1, Pim-2 and Pim-3. They play a critical role in the control of cell proliferation, survival, homing and migration. Recently, overexpression of Pim kinases has been reported...

Descripción completa

Detalles Bibliográficos
Autores principales: Mondello, Patrizia, Cuzzocrea, Salvatore, Mian, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266197/
https://www.ncbi.nlm.nih.gov/pubmed/25491234
http://dx.doi.org/10.1186/s13045-014-0095-z