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Pim kinases in hematological malignancies: where are we now and where are we going?
The proviral insertion in murine (PIM) lymphoma proteins are a serine/threonine kinase family composed of three isoformes: Pim-1, Pim-2 and Pim-3. They play a critical role in the control of cell proliferation, survival, homing and migration. Recently, overexpression of Pim kinases has been reported...
Autores principales: | Mondello, Patrizia, Cuzzocrea, Salvatore, Mian, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266197/ https://www.ncbi.nlm.nih.gov/pubmed/25491234 http://dx.doi.org/10.1186/s13045-014-0095-z |
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