Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts

BACKGROUND: The presence of somatic mutations in splicing factor 3b subunit 1 (SF3B1) in patients with Myelodysplastic syndromes with ring sideroblasts (MDS-RS) highlights the importance of the RNA-splicing machinery in MDS. We previously reported the presence of bone marrow (BM) RS in Sf3b1 heteroz...

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Detalles Bibliográficos
Autores principales: Visconte, Valeria, Tabarroki, Ali, Zhang, Li, Parker, Yvonne, Hasrouni, Edy, Mahfouz, Reda, Isono, Kyoichi, Koseki, Haruhiko, Sekeres, Mikkael A, Saunthararajah, Yogen, Barnard, John, Lindner, Daniel, Rogers, Heesun J, Tiu, Ramon V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266210/
https://www.ncbi.nlm.nih.gov/pubmed/25481243
http://dx.doi.org/10.1186/s13045-014-0089-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266210/
https://www.ncbi.nlm.nih.gov/pubmed/25481243
http://dx.doi.org/10.1186/s13045-014-0089-x

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