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Quantum dots immunofluorescence histochemical detection of EGFR gene mutations in the non-small cell lung cancers using mutation-specific antibodies

BACKGROUND: Epidermal growth factor receptor (EGFR) mutation status plays an important role in therapeutic decision making for non-small cell lung cancer (NSCLC) patients. Since EGFR mutation-specific antibodies (E746-A750del and L858R) have been developed, EGFR mutation detection by immunohistochem...

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Detalles Bibliográficos
Autores principales: Qu, Yan-Gang, Zhang, Qian, Pan, Qi, Zhao, Xian-Da, Huang, Yan-Hua, Chen, Fu-Chun, Chen, Hong-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266265/
https://www.ncbi.nlm.nih.gov/pubmed/25525358
http://dx.doi.org/10.2147/IJN.S71310