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In Vitro and in Vivo Evaluation of Water-Soluble Iminophosphorane Ruthenium(II) Compounds. A Potential Chemotherapeutic Agent for Triple Negative Breast Cancer

[Image: see text] A series of organometallic ruthenium(II) complexes containing iminophosphorane ligands have been synthesized and characterized. Cationic compounds with chloride as counterion are soluble in water (70–100 mg/mL). Most compounds (especially highly water-soluble 2) are more cytotoxic...

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Detalles Bibliográficos
Autores principales: Frik, Malgorzata, Martínez, Alberto, Elie, Benelita T., Gonzalo, Oscar, Ramírez de Mingo, Daniel, Sanaú, Mercedes, Sánchez-Delgado, Roberto, Sadhukha, Tanmoy, Prabha, Swayam, Ramos, Joe W., Marzo, Isabel, Contel, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266334/
https://www.ncbi.nlm.nih.gov/pubmed/25409416
http://dx.doi.org/10.1021/jm5012337