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Preparation, Pharmacokinetics, Biodistribution, Antitumor Efficacy and Safety of Lx2-32c-Containing Liposome

Lx2-32c is a novel taxane that has been demonstrated to have robust antitumor activity against different types of tumors including several paclitaxel-resistant neoplasms. Since the delivery vehicles for taxane, which include cremophor EL, are all associated with severe toxic effects, liposome-based...

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Detalles Bibliográficos
Autores principales: Wang, Hongbo, Zhang, Jianqiao, Lv, Guangyao, Ma, Jinbo, Ma, Pengkai, Du, Guangying, Wang, Zongliang, Tian, Jingwei, Fang, Weishuo, Fu, Fenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266495/
https://www.ncbi.nlm.nih.gov/pubmed/25506928
http://dx.doi.org/10.1371/journal.pone.0114688