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Cytotoxic Effects of Tetracycline Analogues (Doxycycline, Minocycline and COL-3) in Acute Myeloid Leukemia HL-60 Cells

Tetracycline analogues (TCNAs) have been shown to inhibit matrix metalloproteinases and to induce apoptosis in several cancer cell types. In the present study, the cytotoxic effects of TCNAs doxycycline (DOXY), minocycline (MINO) and chemically modified tetracycline-3 (COL-3) were investigated in th...

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Detalles Bibliográficos
Autores principales: Song, Hairong, Fares, Mona, Maguire, Kim R., Sidén, Åke, Potácová, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266609/
https://www.ncbi.nlm.nih.gov/pubmed/25502932
http://dx.doi.org/10.1371/journal.pone.0114457