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Avidity of Anti-Circumsporozoite Antibodies following Vaccination with RTS,S/AS01(E) in Young Children

BACKGROUND: The nature of protective immune responses elicited by immunization with the candidate malaria vaccine RTS,S is still incompletely understood. Antibody levels correlate with protection against malaria infection, but considerable variation in outcome is unexplained (e.g., children may expe...

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Detalles Bibliográficos
Autores principales: Olotu, Ally, Clement, Frederic, Jongert, Erik, Vekemans, Johan, Njuguna, Patricia, Ndungu, Francis M., Marsh, Kevin, Leroux-Roels, Geert, Bejon, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266636/
https://www.ncbi.nlm.nih.gov/pubmed/25506706
http://dx.doi.org/10.1371/journal.pone.0115126