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Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model

Ovalbumin (OVA)-sensitized BALB/c mice were i.n. instilled with recombinant TNF-related apoptosis inducing ligand (TRAIL) 24 hours before OVA challenge. The total number of leukocytes and the levels of the chemokine CXCL-1/KC significantly increased in the bronchoalveolar lavage (BAL) fluids of alle...

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Detalles Bibliográficos
Autores principales: Tisato, Veronica, Garrovo, Chiara, Biffi, Stefania, Petrera, Francesca, Voltan, Rebecca, Casciano, Fabio, Meroni, Germana, Agnoletto, Chiara, Zauli, Giorgio, Secchiero, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266651/
https://www.ncbi.nlm.nih.gov/pubmed/25506835
http://dx.doi.org/10.1371/journal.pone.0115387