Evodiamine Induces G2/M Arrest and Apoptosis via Mitochondrial and Endoplasmic Reticulum Pathways in H446 and H1688 Human Small-Cell Lung Cancer Cells

The goal of this study was to evaluate the ability of EVO to decrease cell viability and promote cell cycle arrest and apoptosis in small cell lung cancer (SCLC) cells. Lung cancer has the highest incidence and mortality rates among all cancers. Chemotherapy is the primary treatment for SCLC; howeve...

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Detalles Bibliográficos
Autores principales: Fang, Chunshu, Zhang, Jingqing, Qi, Di, Fan, Xiaoqing, Luo, Jianchun, Liu, Ling, Tan, Qunyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266682/
https://www.ncbi.nlm.nih.gov/pubmed/25506932
http://dx.doi.org/10.1371/journal.pone.0115204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266682/
https://www.ncbi.nlm.nih.gov/pubmed/25506932
http://dx.doi.org/10.1371/journal.pone.0115204

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