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Evodiamine Induces G2/M Arrest and Apoptosis via Mitochondrial and Endoplasmic Reticulum Pathways in H446 and H1688 Human Small-Cell Lung Cancer Cells
The goal of this study was to evaluate the ability of EVO to decrease cell viability and promote cell cycle arrest and apoptosis in small cell lung cancer (SCLC) cells. Lung cancer has the highest incidence and mortality rates among all cancers. Chemotherapy is the primary treatment for SCLC; howeve...
Autores principales: | Fang, Chunshu, Zhang, Jingqing, Qi, Di, Fan, Xiaoqing, Luo, Jianchun, Liu, Ling, Tan, Qunyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266682/ https://www.ncbi.nlm.nih.gov/pubmed/25506932 http://dx.doi.org/10.1371/journal.pone.0115204 |
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