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Oral effectiveness of PMIC4, a novel hydroxyethylpiperazine analogue, in Leishmania amazonensis

Pentavalent antimonials have saved the lives of thousands of Leishmania-infected patients more than seventy years but, unfortunately, they are highly toxic and require parenteral delivery. Therefore, the search for safer and orally delivered alternative is a need. This paper describes the antileishm...

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Detalles Bibliográficos
Autores principales: Vasconcelos, Mariela Ferreira de, Cunha-Júnior, Edézio Ferreira da, Andrade-Neto, Valter Viana de, Siqueira, Larissa Moreira, d’Avila-Levy, Cláudia Masini, Moreth, Marcele, Cunico, Wilson, Souza, Marcus Vinícius Nora de, Gomes, Cláudia Regina Brandão, Torres-Santos, Eduardo Caio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266774/
https://www.ncbi.nlm.nih.gov/pubmed/25516829
http://dx.doi.org/10.1016/j.ijpddr.2014.10.005