Compound library screening identified Akt/PKB kinase pathway inhibitors as potential key molecules for the development of new chemotherapeutics against schistosomiasis

Protein kinases (PKs) are one of the largest protein families in most eukaryotic organisms. These enzymes are involved in the control of cell proliferation, differentiation and metabolism and a large number of the anticancer drugs currently used are directed against PKs. The structure and function o...

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Detalles Bibliográficos
Autores principales: Morel, Marion, Vanderstraete, Mathieu, Cailliau, Katia, Lescuyer, Arlette, Lancelot, Julien, Dissous, Colette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266776/
https://www.ncbi.nlm.nih.gov/pubmed/25516836
http://dx.doi.org/10.1016/j.ijpddr.2014.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266776/
https://www.ncbi.nlm.nih.gov/pubmed/25516836
http://dx.doi.org/10.1016/j.ijpddr.2014.09.004

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