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Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug

Schistosomiasis is a neglected tropical disease caused by blood-dwelling flukes of the genus Schistosoma. While the disease may affect as many as 249 million people, treatment largely relies on a single drug, praziquantel. The near exclusive use of this drug for such a prevalent disease has led to c...

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Detalles Bibliográficos
Autores principales: Mwangi, Ibrahim N., Sanchez, Melissa C., Mkoji, Gerald M., Agola, Lelo E., Runo, Steven M., Cupit, Pauline M., Cunningham, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266778/
https://www.ncbi.nlm.nih.gov/pubmed/25516840
http://dx.doi.org/10.1016/j.ijpddr.2014.09.006