Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics

Pharmacological targeting of glutamate-gated chloride channels (GluCls) is a potent anthelmintic strategy, evidenced by macrocyclic lactones that eliminate numerous roundworm infections by activating roundworm GluCls. Given the recent identification of flatworm GluCls and the urgent need for drugs a...

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Detalles Bibliográficos
Autores principales: Lynagh, Timothy, Cromer, Brett A., Dufour, Vanessa, Laube, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266781/
https://www.ncbi.nlm.nih.gov/pubmed/25516835
http://dx.doi.org/10.1016/j.ijpddr.2014.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266781/
https://www.ncbi.nlm.nih.gov/pubmed/25516835
http://dx.doi.org/10.1016/j.ijpddr.2014.07.004

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