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Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics
Pharmacological targeting of glutamate-gated chloride channels (GluCls) is a potent anthelmintic strategy, evidenced by macrocyclic lactones that eliminate numerous roundworm infections by activating roundworm GluCls. Given the recent identification of flatworm GluCls and the urgent need for drugs a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266781/ https://www.ncbi.nlm.nih.gov/pubmed/25516835 http://dx.doi.org/10.1016/j.ijpddr.2014.07.004 |