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Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis

Lymphatic filariasis and onchocerciasis are debilitating diseases caused by parasitic filarial nematodes infecting around 150 million people throughout the tropics with more than 1.5 billion at risk. As with other neglected tropical diseases, classical drug-discovery and development is lacking and a...

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Detalles Bibliográficos
Autores principales: Johnston, Kelly L., Ford, Louise, Umareddy, Indira, Townson, Simon, Specht, Sabine, Pfarr, Kenneth, Hoerauf, Achim, Altmeyer, Ralf, Taylor, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266796/
https://www.ncbi.nlm.nih.gov/pubmed/25516838
http://dx.doi.org/10.1016/j.ijpddr.2014.09.001