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Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?

Drug discovery programs sponsored by public or private initiatives pursue the same ambitious goal: a crushing defeat of major Neglected Tropical Diseases (NTDs) during this decade. Both target-based and target-free screenings have pros and cons when it comes to finding potential small-molecule leads...

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Detalles Bibliográficos
Autores principales: Reguera, Rosa M., Calvo-Álvarez, Estefanía, Álvarez-Velilla, Raquel, Balaña-Fouce, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266804/
https://www.ncbi.nlm.nih.gov/pubmed/25516847
http://dx.doi.org/10.1016/j.ijpddr.2014.05.001