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Protonophore properties of hyperforin are essential for its pharmacological activity

Hyperforin is a pharmacologically active component of the medicinal plant Hypericum perforatum (St. John's wort), recommended as a treatment for a range of ailments including mild to moderate depression. Part of its action has been attributed to TRPC6 channel activation. We found that hyperfori...

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Detalles Bibliográficos
Autores principales: Sell, Thomas S., Belkacemi, Thabet, Flockerzi, Veit, Beck, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266863/
https://www.ncbi.nlm.nih.gov/pubmed/25511254
http://dx.doi.org/10.1038/srep07500