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Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release

GDP release from GTPases is usually extremely slow and is in general assisted by external factors, such as association with guanine exchange factors or membrane-embedded GPCRs (G protein-coupled receptors), which accelerate the release of GDP by several orders of magnitude. Intrinsic factors can als...

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Detalles Bibliográficos
Autores principales: Guilfoyle, Amy P., Deshpande, Chandrika N., Schenk, Gerhard, Maher, Megan J., Jormakka, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266920/
https://www.ncbi.nlm.nih.gov/pubmed/25374115
http://dx.doi.org/10.1042/BSR20140152