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Mixed lineage leukaemia histone methylases 1 collaborate with ERα to regulate HOXA10 expression in AML

HOXA10, a homeobox-containing gene involved in definitive haematopoiesis, which implicated in the pathogenesis of AML (acute myeloid leukaemia), has been studied extensively. But the regulatory mechanism that drives HOXA10 expression is still unclear. In the present paper, HOXA10 regulated by MLL1 (...

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Detalles Bibliográficos
Autores principales: Yao, Jie, Fang, Li-Chao, Yang, Zai-Lin, Huang, Hui, Li, Yan, Deng, Jun, Zheng, Junsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266925/
https://www.ncbi.nlm.nih.gov/pubmed/25307539
http://dx.doi.org/10.1042/BSR20140116