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Insulin renders diabetic rats resistant to acute ischemic stroke by arresting nitric oxide reaction with superoxide to form peroxynitrite

BACKGROUND: The functions of free radicals on the effects of insulin that result in protection against cerebral ischemic insult in diabetes remain undefined. This present study aims to explain the contradiction among nitric oxide (NO)/superoxide/peroxynitrite of insulin in amelioration of focal cere...

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Detalles Bibliográficos
Autores principales: Hung, Li-Man, Huang, Jiung-Pang, Liao, Jiuan-Miaw, Yang, Meng-Hsuan, Li, Dai-Er, Day, Yuan-Ji, Huang, Shiang-Suo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266964/
https://www.ncbi.nlm.nih.gov/pubmed/25223305
http://dx.doi.org/10.1186/s12929-014-0092-0