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Insulin renders diabetic rats resistant to acute ischemic stroke by arresting nitric oxide reaction with superoxide to form peroxynitrite
BACKGROUND: The functions of free radicals on the effects of insulin that result in protection against cerebral ischemic insult in diabetes remain undefined. This present study aims to explain the contradiction among nitric oxide (NO)/superoxide/peroxynitrite of insulin in amelioration of focal cere...
Autores principales: | Hung, Li-Man, Huang, Jiung-Pang, Liao, Jiuan-Miaw, Yang, Meng-Hsuan, Li, Dai-Er, Day, Yuan-Ji, Huang, Shiang-Suo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266964/ https://www.ncbi.nlm.nih.gov/pubmed/25223305 http://dx.doi.org/10.1186/s12929-014-0092-0 |
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