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E5564 inhibits immunosuppressive cytokine IL-10 induction promoted by HIV-1 Tat protein

BACKGROUND: In HIV-1 infected patients, production of interleukin-10 (IL-10), a highly immunosuppressive cytokine, is associated with progression of infection toward AIDS. HIV-1 Tat protein, by interacting with TLR4-MD2 at the membrane level, induces IL-10 production by primary human monocytes and m...

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Detalles Bibliográficos
Autores principales:	Bahraoui, Elmostafa, Briant, Laurence, Chazal, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267154/ https://www.ncbi.nlm.nih.gov/pubmed/25471526 http://dx.doi.org/10.1186/s12985-014-0214-z

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