Thromboxane A2 acts as tonic immunoregulator by preferential disruption of low-avidity CD4(+) T cell–dendritic cell interactions

Interactions between dendritic cells (DCs) and T cells control the decision between activation and tolerance induction. Thromboxane A2 (TXA2) and its receptor TP have been suggested to regulate adaptive immune responses through control of T cell–DC interactions. Here, we show that this control is ac...

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Detalles Bibliográficos
Autores principales: Moalli, Federica, Cupovic, Jovana, Thelen, Flavian, Halbherr, Pascal, Fukui, Yoshinori, Narumiya, Shuh, Ludewig, Burkhard, Stein, Jens V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267235/
https://www.ncbi.nlm.nih.gov/pubmed/25488981
http://dx.doi.org/10.1084/jem.20140137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267235/
https://www.ncbi.nlm.nih.gov/pubmed/25488981
http://dx.doi.org/10.1084/jem.20140137

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