Dynamic changes in E-protein activity regulate T reg cell development

E-proteins are TCR-sensitive transcription factors essential for intrathymic T cell transitions. Here, we show that deletion of E-proteins leads to both enhanced peripheral TGF-β–induced regulatory T (iT reg) cell and thymic naturally arising T reg cell (nT reg cell) differentiation. In contrast, de...

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Detalles Bibliográficos
Autores principales: Gao, Ping, Han, Xiaojuan, Zhang, Qi, Yang, Zhiqiong, Fuss, Ivan J., Myers, Timothy G., Gardina, Paul J., Zhang, Fuping, Strober, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267236/
https://www.ncbi.nlm.nih.gov/pubmed/25488982
http://dx.doi.org/10.1084/jem.20132681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267236/
https://www.ncbi.nlm.nih.gov/pubmed/25488982
http://dx.doi.org/10.1084/jem.20132681

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