CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation

We used a genome-wide screen in mutagenized mice to identify genes which inactivation protects against lethal neuroinflammation during experimental cerebral malaria (ECM). We identified an ECM-protective mutation in coiled-coil domain containing protein 88b (Ccdc88b), a poorly annotated gene that is...

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Detalles Bibliográficos
Autores principales: Kennedy, James M., Fodil, Nassima, Torre, Sabrina, Bongfen, Silayuv E., Olivier, Jean-Frédéric, Leung, Vicki, Langlais, David, Meunier, Charles, Berghout, Joanne, Langat, Pinky, Schwartzentruber, Jeremy, Majewski, Jacek, Lathrop, Mark, Vidal, Silvia M., Gros, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267237/
https://www.ncbi.nlm.nih.gov/pubmed/25403443
http://dx.doi.org/10.1084/jem.20140455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267237/
https://www.ncbi.nlm.nih.gov/pubmed/25403443
http://dx.doi.org/10.1084/jem.20140455

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