Cargando…
CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow
Leukocyte residence in lymphoid organs is controlled by a balance between retention and egress-promoting chemoattractants sensed by pertussis toxin (PTX)–sensitive Gαi protein–coupled receptors (GPCRs). Here, we use two-photon intravital microscopy to show that immature B cell retention within bone...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267240/ https://www.ncbi.nlm.nih.gov/pubmed/25403444 http://dx.doi.org/10.1084/jem.20140457 |