Revisiting Anti-tuberculosis Activity of Pyrazinamide in Mice

The mechanism of action of pyrazinamide, a key sterilizing drug in the treatment of tuberculosis, remains elusive; pyrazinamide is a pro-drug that requires activation by a bacterial-encoded enzyme, and its activity is most apparent on non-replicating Mycobacterium tuberculosis. Recently, it has been...

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Detalles Bibliográficos
Autores principales: Almeida, Deepak V., Tyagi, Sandeep, Li, Si-Yang, Wallengren, Kristina, Pym, Alexander S., Ammerman, Nicole C., Bishai, William R., Grosset, Jacques H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267256/
https://www.ncbi.nlm.nih.gov/pubmed/25525563
http://dx.doi.org/10.4172/2161-1068.1000145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267256/
https://www.ncbi.nlm.nih.gov/pubmed/25525563
http://dx.doi.org/10.4172/2161-1068.1000145

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