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SMT19969 as a treatment for Clostridium difficile infection: an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model

OBJECTIVES: We investigated the efficacy of the novel antimicrobial agent SMT19969 in treating simulated Clostridium difficile infection using an in vitro human gut model. METHODS: Concentrations of the predominant cultivable members of the indigenous gut microfloras and C. difficile (total and spor...

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Detalles Bibliográficos
Autores principales: Baines, S. D., Crowther, G. S., Freeman, J., Todhunter, S., Vickers, R., Wilcox, M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267497/
https://www.ncbi.nlm.nih.gov/pubmed/25190720
http://dx.doi.org/10.1093/jac/dku324