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qDNAmod: a statistical model-based tool to reveal intercellular heterogeneity of DNA modification from SMRT sequencing data

In an isogenic cell population, phenotypic heterogeneity among individual cells is common and critical for survival of the population under different environment conditions. DNA modification is an important epigenetic factor that can regulate phenotypic heterogeneity. The single molecule real-time (...

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Detalles Bibliográficos
Autores principales: Feng, Zhixing, Li, Jing, Zhang, Jing-Ren, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267614/
https://www.ncbi.nlm.nih.gov/pubmed/25404133
http://dx.doi.org/10.1093/nar/gku1097