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Locating the uracil-5-yl radical formed upon photoirradiation of 5-bromouracil-substituted DNA
In a previous study, we found that 2-deoxyribonolactone is effectively generated in the specific 5-bromouracil ((Br)U)-substituted sequence 5′-(G/C)[A](n) (= 1,2)(Br)U(Br)U-3′ and proposed that a formed uracil-5-yl radical mainly abstracts the C1′ hydrogen from the 5′-side of (Br)U(Br)U under 302-nm...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267621/ https://www.ncbi.nlm.nih.gov/pubmed/25398904 http://dx.doi.org/10.1093/nar/gku1133 |