The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes

The substitution-inert polynuclear platinum(II) complex (PPC) series, [{trans-Pt(NH(3))(2)(NH(2)(CH(2))(n)NH(3))}(2)-μ-(trans-Pt(NH(3))(2)(NH(2)(CH(2))(n)NH(2))(2)}](NO(3))(8), where n = 5 (AH78P), 6 (AH78 TriplatinNC) and 7 (AH78H), are potent non-covalent DNA binding agents where nucleic acid reco...

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Detalles Bibliográficos
Autores principales: Prisecaru, Andreea, Molphy, Zara, Kipping, Ralph G., Peterson, Erica J., Qu, Yun, Kellett, Andrew, Farrell, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267626/
https://www.ncbi.nlm.nih.gov/pubmed/25414347
http://dx.doi.org/10.1093/nar/gku1157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267626/
https://www.ncbi.nlm.nih.gov/pubmed/25414347
http://dx.doi.org/10.1093/nar/gku1157

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