Alanine repeats influence protein localization in splicing speckles and paraspeckles

Mammalian splicing regulatory protein RNA-binding motif protein 4 (RBM4) has an alanine repeat-containing C-terminal domain (CAD) that confers both nuclear- and splicing speckle-targeting activities. Alanine-repeat expansion has pathological potential. Here we show that the alanine-repeat tracts inf...

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Detalles Bibliográficos
Autores principales: Chang, Shuo-Hsiu, Chang, Wei-Lun, Lu, Chia-Chen, Tarn, Woan-Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267627/
https://www.ncbi.nlm.nih.gov/pubmed/25414336
http://dx.doi.org/10.1093/nar/gku1159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267627/
https://www.ncbi.nlm.nih.gov/pubmed/25414336
http://dx.doi.org/10.1093/nar/gku1159

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